Brain tissue from deceased military veterans exposed to explosions shows signs of the same neurodegenerative brain disorder that strikes football players who have sustained multiple concussions.
The stress and suffering of combat are known to leave a lasting impact on military veterans, in some cases triggering post-traumatic stress disorder (PTSD). Researchers have now found an even more serious and debilitating mental condition, known as chronic traumatic encephalopathy(CTE), in veterans, particularly those injured by the concussive force of bomb blasts.
Whereas PTSD is a mental illness, marked by unwelcome flashbacks and anguish, CTE is a progressive neurodegenerative brain disorder characterized by abnormal protein deposits that eventually kill brain cells and thus cause cognitive declines, including loss of memory and the ability to learn as well asdepression. The number of veterans at risk is large: traumatic brain injury caused by explosive blasts is thought to afflict about 20 percent of the 2.3 million servicemen and women deployed in combat since 2001, according to a team of researchers from Boston University, New York Medical College and the Veterans Affairs Boston Healthcare System.
These researchers say they have demonstrated that exposure to a single blast equivalent to that generated by a typical improvised explosive device (IED) can result in CTE and long-term brain impairments that accompany the disease. The research, published online Wednesday in Science Translational Medicine, also indicates that soldiers are injured by more than just the initial shock wave of very high air pressure following a blast. An IED's secondary "blast wind," a huge volume of displaced air flooding at high pressure back into the vacuum, can also damage the brain and lead to long-term consequences such as CTE. The blast wind created by an IED can reach a velocity of more than 530 kilometers per hour. Winds from a category 5 hurricane (the most severe), by comparison, reach about 250 kilometers per hour. More